TIRZEPATIDE 10 & 20mg
- ≥99% purity by HPLC
- Janoshik COA with every lot
- Lot-traceable from synthesis
- EU-synthesised
Specifications
Third Party Lab Tested
Every lot is independently HPLC-tested by Janoshik Analytical, Europe's reference laboratory for peptide purity assessment. The COA shipped with your order is theirs, not ours.
Storage & Handling
Lyophilized peptides should be stored below 16°C, protected from light and moisture, for up to 24 months. Once reconstituted, refrigerate and use within 30 days for protocol consistency.
Reconstitution
Reconstitute with bacteriostatic water using the volumes below. Add solvent slowly along the inside wall of the vial. Swirl gently, never shake, until fully dissolved.
Lab-handling protocol BAC Water · 0.9% benzyl alcohol The reconstitution solvent referenced above. Add to order →Dual-receptor incretin research.
Tirzepatide is a 39-amino-acid synthetic peptide characterised as a dual agonist at the GLP-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). This two-receptor profile places Tirzepatide between single-pathway Semaglutide and triple-agonist Retatrutide in incretin and metabolic-signalling research. This variable product supplies 10 MG or 20 MG lyophilized research vials within the NZM-Labs research peptide range.
Every production lot is independently analysed by HPLC and mass spectrometry, with lot-specific documentation available for matching the vial to its analytical record. For laboratory research only.
| Compound | Tirzepatide |
|---|---|
| Sequence length | 39 amino acids |
| Molecular mass | 4813.5 Da |
| Modeled half-life | ~5 days (modeled) |
| Mechanism / research class | Dual GLP-1R / GIPR agonist |
| Example laboratory preparation | 10 MG or 20 MG vial with 2 mL bacteriostatic water (0.9% benzyl alcohol) |
| Calculated concentration | 10 MG: 5 mg per 1.0 mL; 20 MG: 10 mg per 1.0 mL |
| Supply format | Tirzepatide · 10 MG or 20 MG lyophilized research vial |
| Storage, lyophilized | store below 16°C for up to 24 months |
| Storage, reconstituted | refrigerate and use within 30 days |
Synthesised.
Verified.
Documented.
Backed by research.
Measured in results.
Each tag opens the cited literature behind that effect. References are linked to PubMed.
Tirzepatide is a 39-amino-acid GLP-1 / GIP dual agonist. The dual receptor profile produces a steeper satiety-pathway response than single-pathway GLP-1, with downstream effects on body weight and adiposity in both research models and published clinical literature.
The reference SURMOUNT-1 trial reported a mean body-weight reduction of −22.5% from baseline at 72 weeks in the highest published study arm, with monotonic responses across published study arms. Results referenced for in-vitro / animal-model protocol design only.
GLP-1 / GIP dual agonism amplifies insulin secretion and steepens the glycemic-response curve compared with single-pathway GLP-1 agonism. The reference literature reports HbA1c reductions of 1.87% to 2.59% across published weekly study arms in T2D research populations.
- Rosenstock J et al. Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes. The Lancet. 2021;398(10295):143-155. PubMed ↗
GLP-1 / GIP co-agonism engages hepatic lipid handling beyond what GLP-1 alone produces. The Tirzepatide MASLD substudy reported relative liver-fat reduction of up to 73% at 52 weeks measured by MRI-PDFF in the highest published study arm.
- Hartman ML et al. Effects of tirzepatide on biomarkers of NAFLD/NASH in patients with T2D. Diabetes Care. 2020;43(6):1352-1355. PubMed ↗
Beyond direct glycemic effects, dual incretin agonism improves measured markers of insulin sensitivity (HOMA-IR) and metabolic flexibility in research populations - a profile that distinguishes Tirzepatide from single-pathway references in published comparison studies.
- Frías JP et al. SURPASS-2 trial. NEJM. 2021;385(6):503-515. PubMed ↗
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